Nanoparticle-based drug delivery is a promising method to increase the therapeutic index of anti-cancer agents with low median toxic dose. The delivery effic...

The integral simplex using decomposition (ISUD) algorithm was recently developed to solve efficiently set partitioning problems containing a number of variab...

The bid construction problem (BCP) for combinatorial total truckload transportation service procurement auctions consists of determining one or several bids ...

This paper deals with R&D investment and technology licensing in a supply chain formed of an original equipment manufacturer (OEM) and a contract manufactu...

A performance-based mechanism as a support for an environmental protection law is proposed to promote product recovery and to subside the pollution caused by...

In this paper, we evaluate the competitiveness of electric commercial vehicle (ECV) in medium-duty mid-haul logistics for a specific case study. This is done...

Electric commercial vehicles (ECVs) are gaining importance as they are seen to provide a sustainable mean of transportation. However, practitioners still see...

This paper reviews the literature on vehicle routing problems and location-routing problems with intermediate stops. Besides providing concise paper excerpts...

The purpose of this paper is to develop a fast heuristic called FastCARP for the solution of very large-scale capacitated arc routing problems, with or witho...

Management and storage of waste and tailings are critical concerns in open pit mining, especially when the available space is limited but also to reduce the ...

Long-term open pit mine scheduling is generally assessed with a mixed integer programming (MIP) formulation which can be solved with different operations res...

The airline crew scheduling problem, because of its size and complexity, is usually solved in two phases: the crew pairing problem and the crew assignment pr...

Scheduling problems on which constraints are imposed with regard to the temporal distances between successive executions of the same task have numerous appli...

In this article we consider a bi-objective vehicle routing problem in which, in addition to the classical minimization of the total routing cost, the operato...

We consider a static team problem in which agents observe correlated Gaussian observations and seek to minimize a quadratic cost. It is assumed that the ob...

Personnel scheduling consists of determining least-cost employee work schedules to cover the demand of one or several jobs in each period of a time horizon. ...

Most papers on digital advertising focus on the point of view of Internet companies such as Google and Microsoft, and were written by people working for thos...

This paper proposes a hierarchical decision making model for a coupled planning and operation problem of an advanced microgrid. The proposed model, is formul...

Location-routing problems (LRPs) with intra-route facilities have recently gained the attention of researchers and practitioners. Intra-route facilities are ...

The Runge-Kutta class of iterative methods is designed to approximate solutions of a system of ordinary differential equations (ODE). The second-order cla...