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G-2001-35

Exact Analysis of a Paired Sibling Study

and

BibTeX reference

A data set on categories of congenital heart malformations for sibling pairs (with different malformations) of Fraser and Hunter (1975) is analyzed exactly for quasi-independence with Monte Carlo methods. Exact p-values are computed for a test of parameter significance and a test of goodness-of-fit which contradict the model of quasi-independence and confirm an earlier analysis of MacGibbon (1983).

, 11 pages

Publication

Exact analysis of a paired sibling study
and
Computational Statistics, 19, 525–534, 2004 BibTeX reference